Long-term risk estimates provide novel information regarding risk prediction that is not obtained through modifications of the 10-year risk window. In collaboration with investigators at Northwestern University, we have pooled individual-level data from participants in multiple, unique observational cohorts to create the Cardiovascular Lifetime Risk Pooling Project. Our objective is to determine the lifetime risks for cardiovascular disease death, fatal/non-fatal coronary heart disease, and fatal/non-fatal stroke for risk factors measured at four index ages: age 45-, 55-, 65-, and 75-years. We believe that these findings could be useful for practicing clinicians to identify novel groups of individuals for more intensive lifestyle or pharmacologic preventive interventions.
